Pichia pastoris as One of the Best Choice for Expression of Biopharmaceutical Proteins

authors:

avatar Masoud Keikha ORCID 1 , *

Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
International Journal of Health and Life Sciences: Vol.5, issue 1; e87190
published online: January 13, 2019
article type: Letter
received: December 8, 2018
revised: January 6, 2019
accepted: January 8, 2019
DOI: https://doi.org/10.5812/ijhls.87190

how to cite: Keikha M. Pichia pastoris as One of the Best Choice for Expression of Biopharmaceutical Proteins. J Health Rep Technol. 2019;5(1):e87190. https://doi.org/10.5812/ijhls.87190.

References

  • 1.

    Vogl T, Hartner FS, Glieder A. New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris. Curr Opin Biotechnol. 2013;24(6):1094-101. [PubMed ID: 23522654]. [PubMed Central ID: PMC3841573]. https://doi.org/10.1016/j.copbio.2013.02.024.

  • 2.

    Potvin G, Ahmad A, Zhang Z. Bioprocess engineering aspects of heterologous protein production in Pichia pastoris: A review. Biochem Eng J. 2012;64:91-105. https://doi.org/10.1016/j.bej.2010.07.017.

  • 3.

    Li P, Anumanthan A, Gao XG, Ilangovan K, Suzara VV, Duzgunes N, et al. Expression of recombinant proteins in Pichia pastoris. Appl Biochem Biotechnol. 2007;142(2):105-24. [PubMed ID: 18025573].

  • 4.

    Goodman M. Market watch: Sales of biologics to show robust growth through to 2013. Nat Rev Drug Discov. 2009;8(11):837. [PubMed ID: 19876035]. https://doi.org/10.1038/nrd3040.

  • 5.

    Cregg JM, Cereghino JL, Shi J, Higgins DR. Recombinant protein expression in Pichia pastoris. Mol Biotechnol. 2000;16(1):23-52. [PubMed ID: 11098467]. https://doi.org/10.1385/MB:16:1:23.

  • 6.

    Prielhofer R, Cartwright SP, Graf AB, Valli M, Bill RM, Mattanovich D, et al. Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level. BMC Genomics. 2015;16:167. [PubMed ID: 25887254]. [PubMed Central ID: PMC4408588]. https://doi.org/10.1186/s12864-015-1393-8.

  • 7.

    Darby RA, Cartwright SP, Dilworth MV, Bill RM. Which yeast species shall I choose? Saccharomyces cerevisiae versus Pichia pastoris (review). Methods Mol Biol. 2012;866:11-23. [PubMed ID: 22454110]. https://doi.org/10.1007/978-1-61779-770-5_2.

  • 8.

    Kamal S, Khan SU, Muhammad N, Shoaib M, Omar M, Pascal K, et al. Insights on heterologous expression of fungal cellulases in Pichia pastoris. Biochem Mol Biol. 2018;3(1):15. https://doi.org/10.11648/j.bmb.20180301.13.