Non Surgical Treatment of Sacral Osteosarcoma


avatar Seyed Amir Aledavood 1 , * , avatar A Amirabadi 2 , avatar B Memar 3

1 Cancer Research Center , Mashhad University of Medical Sciences, Mashhad, Iran

2 Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

3 Omid Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

How to Cite: Aledavood S A, Amirabadi A, Memar B. Non Surgical Treatment of Sacral Osteosarcoma. Int J Cancer Manag. 2012;5(1):e80797.


International Journal of Cancer Management: 5 (1); e80797
Published Online: March 31, 2012
Article Type: Case Report
Received: November 03, 2010
Accepted: January 10, 2011


Osteosarcoma may rarely originate from the axial bones such as pelvis or vertebrae. In some pelvic and most vertebral primary tumors, resection often is not possible completely. In general, these tumors cannot be resected with negative margins so they need additional radiotherapy and chemotherapy, but results are unfavourable because of poor local control and high incidence of distant metastases. This is a case report of sacral osteosarcoma which was treated successfully with chemotherapy and radiation therapy. The patient is a 14-year-old boy with a large osteosarcoma tumor in the first sacral vertebral body, with extra skeletal extension. The patient took radiotherapy (6000 centigray) plus chemotherapy regimen consisting of doxorubicin and cisplatin. In the last follow up 48 months later, the patient was completely asymptomatic with normal performance and there was not any evidence of local progression or distant metastasis.


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