Clinicopathological Features of Gastric Cancer: A Study Based on Cancer Registry Data


avatar A Safaee 1 , avatar Bijan Moghimi-Dehkordi 1 , * , avatar SR Fatemi 1 , avatar S Ghiasi 1 , avatar MA Pourhoseingholi 1 , avatar MR Zali 2

1 Research Center of Gastroenterology and Liver Diseases, Shahid Beheshti University (M.C), Tehran, Iran

2 Professor of Gastroentrology, Shahid Beheshti University (M.C), Tehran, Iran

How to Cite: Safaee A, Moghimi-Dehkordi B , Fatemi S, Ghiasi S, Pourhoseingholi M, et al. Clinicopathological Features of Gastric Cancer: A Study Based on Cancer Registry Data. Int J Cancer Manag. 2009;2(2):e80529.


International Journal of Cancer Management: 2 (2); e80529
Published Online: June 30, 2009
Article Type: Research Article
Received: June 30, 2009
Accepted: June 30, 2009


Aim: To analysis the epidemiological and clinopathological aspects of gastric cancer.

Methods: We retrospectively studied the characteristics of 752 gastric carcinoma patients registered in cancer registry center of Taleghani hospital from 2001 to 2006. All the patients confirmed gastric cancer histopathologically. Univariate methods (Mann-Whitney U-test, and chi-square) were used for analysis.

Results: Among 752 cases, 535 (71.1%) were male. Sex ratio (male: female) was 2.49:1. The mean age of the patients was 59.7 years (SD = 12.9) at the time of the diagnosis. Weight loss, as a frequent symptom at the time of diagnosis, was observed in 57.7% of the cases. Most of the patients were diagnosed with advanced pathologic stage. In addition, tumor grading was poorly differentiated in most cases (28.7%) ; and in 49.9% of the patients, the tumors were located in the stomach, NOS ; and distant metastasis was observed in 24.6% of the cases.

Conclusions: Based on the results, earlier detection in younger ages and in primary stages of tumor, and subsequent higher quality care to cure GC and increase patients' life expectancy are recommended.


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